HitPredict

Interactor 1: KLHL2 (O95198)
Kelch-like protein 2 (Actin-binding protein Mayven)
Gene: KLHL2

Interactor 2: TRIM9 (Q9C026)
E3 ubiquitin-protein ligase TRIM9 (EC 2.3.2.27) (RING finger protein 91) (RING-type E3 ubiquitin transferase TRIM9) (Tripartite motif-containing protein 9)
Gene: TRIM9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0016567 - protein ubiquitination
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 593 Hs			1 710
+	Hs
		1261122 KLHL9_HUMAN (14-588): 2.76e-161: 476: 26.86		TRI41_HUMAN (1-693): 3.14e-74: 253: 12.23
+	Hs
		1049242 KEAP1_HUMAN (146-593): 8.68e-52: 189: 23.88		TRI67_HUMAN (4-700): 4.16e-154: 467: 60.98
+	Hs
		1172082 KLH13_HUMAN (449-593): 6.27e-29: 123: 32.67		TRI67_HUMAN (4-700): 4.16e-154: 467: 60.98
+	Hs
		1049207 KEAP1_HUMAN (146-593): 8.68e-52: 189: 23.88		TRI25_HUMAN (77-694): 1.29e-70: 244: 14.87
+	Hs
		301812 KEAP1_HUMAN (146-593): 8.68e-52: 189: 23.88		TRI37_HUMAN (156-519): 2.44e-43: 170: 20.56
+	Hs
		1357688 KLH20_HUMAN (494-593): 2.37e-25: 112: 45.00		TRI33_HUMAN (81-461): 1.69e-60: 222: 14.92
+	Hs
		1299554 KLHL5_HUMAN (428-593): 6.92e-37: 148: 37.13		TRIM2_HUMAN (8-709): 7.28e-24: 109: 11.17
+	Hs
		1233690 KLH36_HUMAN (384-593): 1.42e-35: 143: 23.39		TRI55_HUMAN (1-56): 1.37e-09: 63.3: 35.09
+	Hs
		1233687 KLH36_HUMAN (384-593): 1.42e-35: 143: 23.39		TRI63_HUMAN (1-56): 8.27e-10: 63: 36.84