Interactor 1: KLHL2 (O95198)
Kelch-like protein 2 (Actin-binding protein Mayven)
Gene: KLHL2

Interactor 2: KLHL3 (Q9UH77)
Kelch-like protein 3
Gene: KLHL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.79 1.00 0.894

The method score is based on:

Property Details
Experiments 28514442, 32296183, 33961781, unassigned1304
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains BACK~BTB, BTB~BTB, Kelch_1~Kelch_1
Common GO terms GO:0003779 - actin binding
GO:0005829 - cytosol
GO:0016567 - protein ubiquitination
GO:0031463 - Cul3-RING ubiquitin ligase complex
GO:1990756 - ubiquitin-like ligase-substrate adaptor activity
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 593
Hs

1 587
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Last updated: 15 Jul 2024