HitPredict

Interactor 1: RCBT2 (O95199)
RCC1 and BTB domain-containing protein 2 (Chromosome condensation 1-like) (CHC1-L) (RCC1-like G exchanging factor) (Regulator of chromosome condensation and BTB domain-containing protein 2)
Gene: RCBTB2

Interactor 2: Q7KZS0 (Q7KZS0)
SUMO-conjugating enzyme UBC9 (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I)
Gene: UBE2I

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.50	0.470

Property	Details
Experiments	25416956
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 551 Hs			1 184
+	Hs
		307247 RCBT2_HUMAN (1-551): 2.51e-171: 498: 100.00		UBC9_HUMAN (1-158): 1.17e-69: 210: 86.71
+	Hs
		307269 RCBT2_HUMAN (1-551): 2.51e-171: 498: 100.00		UB2E3_HUMAN (3-156): 2.76e-67: 205: 31.17
+	Hs
		849333 HERC3_HUMAN (2-334): 7.76e-94: 310: 24.72		UB2D1_HUMAN (4-157): 3.15e-74: 221: 31.17
+	Hs
		919733 HERC1_HUMAN (2-222): 1.54e-58: 213: 26.96		UB2D2_HUMAN (4-157): 4.47e-74: 220: 32.47
+	Hs
		895797 HERC1_HUMAN (2-222): 1.54e-58: 213: 26.96		UB2D3_HUMAN (4-157): 8.42e-73: 217: 31.82
+	Hs
		849478 HERC5_HUMAN (2-220): 5.92e-56: 204: 22.59		UB2D1_HUMAN (4-157): 3.15e-74: 221: 31.17
+	Hs
		919895 HERC5_HUMAN (2-220): 5.92e-56: 204: 22.59		UB2D2_HUMAN (4-157): 4.47e-74: 220: 32.47
+	Hs
		895943 HERC5_HUMAN (2-220): 5.92e-56: 204: 22.59		UB2D3_HUMAN (4-157): 8.42e-73: 217: 31.82
+	Hs
		578415 RCC1_HUMAN (12-356): 2.52e-61: 209: 20.00		UBC9_HUMAN (1-158): 1.17e-69: 210: 86.71
+	Hs
		930444 HERC5_HUMAN (2-220): 5.92e-56: 204: 22.59		UBC9_HUMAN (1-158): 1.17e-69: 210: 86.71
+	Hs
		829082 HERC5_HUMAN (2-220): 5.92e-56: 204: 22.59		UBE2A_HUMAN (1-157): 1.19e-68: 207: 36.31
+	Hs
		1282362 HERC5_HUMAN (2-220): 5.92e-56: 204: 22.59		UB2E3_HUMAN (3-156): 2.76e-67: 205: 31.17
+	Hs
		1297377 HERC5_HUMAN (2-220): 5.92e-56: 204: 22.59		UB2E2_HUMAN (3-156): 5.39e-67: 205: 31.17
+	Hs
		927786 HERC5_HUMAN (2-220): 5.92e-56: 204: 22.59		UBE2B_HUMAN (1-155): 1.06e-67: 205: 36.13
+	Hs
		1242535 RCBT1_HUMAN (1-183): 1.26e-44: 167: 24.23		UB2E3_HUMAN (3-156): 2.76e-67: 205: 31.17
+	Mm
		854554 RCBT1_MOUSE (1-183): 9.24e-45: 167: 24.74		UB2E3_MOUSE (3-156): 2.76e-67: 205: 31.17
+	Hs
		919741 HERC4_HUMAN (227-412): 1.79e-23: 107: 22.87		UB2D2_HUMAN (4-157): 4.47e-74: 220: 32.47
+	Hs
		1125824 HERC4_HUMAN (227-412): 1.79e-23: 107: 22.87		UB2E3_HUMAN (3-156): 2.76e-67: 205: 31.17
+	Hs
		828048 HERC5_HUMAN (2-220): 5.92e-56: 204: 22.59		UB2R1_HUMAN (37-137): 5.12e-22: 90.9: 42.86
+	Hs
		891446 HERC5_HUMAN (2-220): 5.92e-56: 204: 22.59		UB2G2_HUMAN (1-137): 1.6e-22: 90.1: 37.16