HitPredict

Interactor 1: EPN2 (O95208)
Epsin-2 (EPS-15-interacting protein 2)
Gene: EPN2

Interactor 2: CLCA (P09496)
Clathrin light chain A (Lca)
Gene: CLTA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	34079125, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0030125 - clathrin vesicle coat
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 641 Hs			1 248
+	Hs
		451438 EPN4_HUMAN (3-638): 3.84e-95: 307: 22.15		CLCA_HUMAN (1-248): 1.53e-98: 289: 100.00
+	Hs
		307498 EPN2_HUMAN (1-641): 7.59e-111: 348: 100.00		CLCB_HUMAN (35-247): 1.52e-67: 210: 60.28
+	Hs
		451676 EPN4_HUMAN (3-638): 3.84e-95: 307: 22.15		CLCB_HUMAN (35-247): 1.52e-67: 210: 60.28
+	Rn
		291385 EPN1_RAT (1-570): 1.18e-64: 224: 39.17		CLCA_RAT (1-248): 7.17e-97: 285: 97.98
+	Hs
		451628 EPN1_HUMAN (1-570): 1.42e-61: 216: 39.27		CLCA_HUMAN (1-248): 1.53e-98: 289: 100.00
+	Hs
		451762 EPN1_HUMAN (1-570): 1.42e-61: 216: 39.27		CLCB_HUMAN (35-247): 1.52e-67: 210: 60.28
+	Hs
		253722 AUXI_HUMAN (227-588): 1.45e-25: 114: 15.48		CLCA_HUMAN (1-248): 1.53e-98: 289: 100.00
+	Hs
		203201 SYNJ1_HUMAN (115-623): 9.93e-22: 102: 13.17		CLCA_HUMAN (1-248): 1.53e-98: 289: 100.00
+	Hs
		253723 AUXI_HUMAN (227-588): 1.45e-25: 114: 15.48		CLCB_HUMAN (35-247): 1.52e-67: 210: 60.28
+	Hs
		203202 SYNJ1_HUMAN (115-623): 9.93e-22: 102: 13.17		CLCB_HUMAN (35-247): 1.52e-67: 210: 60.28