HitPredict

Interactor 1: EPN2 (O95208)
Epsin-2 (EPS-15-interacting protein 2)
Gene: EPN2

Interactor 2: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	33961781, 36931259, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0045296 - cadherin binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 641 Hs			1 245
+	Hs
		307506 EPN2_HUMAN (1-641): 7.59e-111: 348: 100.00		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	Hs
		307510 EPN2_HUMAN (1-641): 7.59e-111: 348: 100.00		1433B_HUMAN (1-242): 9.01e-140: 393: 87.60
+	Hs
		307520 EPN2_HUMAN (1-641): 7.59e-111: 348: 100.00		1433G_HUMAN (1-240): 2.37e-108: 314: 74.59
+	Hs
		307527 EPN2_HUMAN (1-641): 7.59e-111: 348: 100.00		1433F_HUMAN (2-240): 1.26e-107: 312: 74.49
+	Hs
		910018 EPN3_HUMAN (1-636): 9.66e-68: 234: 32.04		1433E_HUMAN (2-241): 9.9e-144: 403: 68.18
+	Hs
		982013 EPN4_HUMAN (3-638): 3.84e-95: 307: 22.15		1433F_HUMAN (2-240): 1.26e-107: 312: 74.49
+	Hs
		927196 OTOG_HUMAN (216-641): 4.64e-30: 129: 13.53		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Hs
		909712 OTOG_HUMAN (216-641): 4.64e-30: 129: 13.53		1433E_HUMAN (2-241): 9.9e-144: 403: 68.18
+	Hs
		647025 OTOG_HUMAN (216-641): 4.64e-30: 129: 13.53		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	Hs
		683472 OTOG_HUMAN (216-641): 4.64e-30: 129: 13.53		1433B_HUMAN (1-242): 9.01e-140: 393: 87.60
+	Hs
		297824 K0754_HUMAN (152-509): 1.09e-24: 112: 11.33		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Hs
		297821 K0754_HUMAN (152-509): 1.09e-24: 112: 11.33		1433E_HUMAN (2-241): 9.9e-144: 403: 68.18
+	Hs
		297815 K0754_HUMAN (152-509): 1.09e-24: 112: 11.33		1433B_HUMAN (1-242): 9.01e-140: 393: 87.60
+	Hs
		904746 OTOG_HUMAN (216-641): 4.64e-30: 129: 13.53		1433G_HUMAN (1-240): 2.37e-108: 314: 74.59
+	Hs
		982175 OTOG_HUMAN (216-641): 4.64e-30: 129: 13.53		1433F_HUMAN (2-240): 1.26e-107: 312: 74.49
+	Hs
		203217 SYNJ1_HUMAN (115-623): 9.93e-22: 102: 13.17		1433G_HUMAN (1-240): 2.37e-108: 314: 74.59
+	Hs
		203222 SYNJ1_HUMAN (115-623): 9.93e-22: 102: 13.17		1433F_HUMAN (2-240): 1.26e-107: 312: 74.49