HitPredict

Interactor 1: EPN2 (O95208)
Epsin-2 (EPS-15-interacting protein 2)
Gene: EPN2

Interactor 2: TRIM1 (Q9UJV3)
Probable E3 ubiquitin-protein ligase MID2 (EC 2.3.2.27) (Midin-2) (Midline defect 2) (Midline-2) (RING finger protein 60) (RING-type E3 ubiquitin transferase MID2) (Tripartite motif-containing protein 1)
Gene: MID2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.50	0.553

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 641 Hs			1 735
+	Hs
		175627 EPN2_HUMAN (1-641): 7.59e-111: 348: 100.00		TRI18_HUMAN (21-717): 8.76e-175: 518: 72.60
+	Hs
		111205 I6L9I8_HUMAN (1-339): 1.48e-107: 329: 45.13		TRI18_HUMAN (21-717): 8.76e-175: 518: 72.60
+	Hs
		1328942 EPN3_HUMAN (1-636): 9.66e-68: 234: 32.04		TRIM1_HUMAN (1-735): 0: 592: 100.00
+	Hs
		175713 EPN3_HUMAN (1-636): 9.66e-68: 234: 32.04		TRI18_HUMAN (21-717): 8.76e-175: 518: 72.60
+	Hs
		307538 EPN2_HUMAN (1-641): 7.59e-111: 348: 100.00		TRI67_HUMAN (74-718): 5.93e-89: 297: 22.96
+	Hs
		1057061 EPN4_HUMAN (3-638): 3.84e-95: 307: 22.15		TRI67_HUMAN (74-718): 5.93e-89: 297: 22.96
+	Hs
		1172486 EPN1_HUMAN (1-570): 1.42e-61: 216: 39.27		TRI67_HUMAN (74-718): 5.93e-89: 297: 22.96
+	Hs
		307561 EPN2_HUMAN (1-641): 7.59e-111: 348: 100.00		TRI62_HUMAN (114-458): 1.79e-32: 133: 15.47
+	Hs
		307511 EPN2_HUMAN (1-641): 7.59e-111: 348: 100.00		TRI23_HUMAN (28-272): 6.41e-17: 86.7: 24.71
+	Hs
		203236 SYNJ1_HUMAN (115-623): 9.93e-22: 102: 13.17		TRI67_HUMAN (74-718): 5.93e-89: 297: 22.96
+	Hs
		1049027 EPN4_HUMAN (3-638): 3.84e-95: 307: 22.15		TRI14_HUMAN (192-413): 5.06e-11: 67.6: 19.30