HitPredict

Interactor 1: LC7L3 (O95232)
Luc7-like protein 3 (Cisplatin resistance-associated-overexpressed protein) (Luc7A) (Okadaic acid-inducible phosphoprotein OA48-18) (cAMP regulatory element-associated protein 1) (CRE-associated protein 1) (CREAP-1)
Gene: LUC7L3

Interactor 2: RNPS1 (Q15287)
RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2)
Gene: RNPS1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.606

Property	Details
Experiments	17353931, 14729963
Identification Methods	affinity chromatography technology, two hybrid, anti bait coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0008380 - RNA splicing GO:0016607 - nuclear speck
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 432 Hs			1 305
+	Sc
		991484 LUC7_YEAST (4-250): 1.36e-56: 189: 25.78		NCBP2_YEAST (127-236): 1.25e-33: 124: 25.46
+	Hs
		1070655 LUC7L_HUMAN (3-369): 3.35e-51: 178: 32.34		RNPS1_HUMAN (1-234): 2e-34: 128: 100.00
+	Hs
		1343078 LUC7L_HUMAN (3-369): 3.35e-51: 178: 32.34		PPIE_HUMAN (159-297): 4.41e-33: 125: 17.73
+	Hs
		1070702 LC7L2_HUMAN (3-402): 2.11e-47: 168: 28.43		RNPS1_HUMAN (1-234): 2e-34: 128: 100.00
+	Hs
		1357566 LC7L2_HUMAN (3-402): 2.11e-47: 168: 28.43		PPIE_HUMAN (159-297): 4.41e-33: 125: 17.73
+	Hs
		1031502 LC7L2_HUMAN (3-402): 2.11e-47: 168: 28.43		PABP4_HUMAN (153-248): 4.98e-19: 89.2: 27.08
+	Hs
		1329991 LC7L2_HUMAN (3-402): 2.11e-47: 168: 28.43		PABP3_HUMAN (153-248): 4.53e-17: 83.4: 26.04