HitPredict

Interactor 1: LC7L3 (O95232)
Luc7-like protein 3 (Cisplatin resistance-associated-overexpressed protein) (Luc7A) (Okadaic acid-inducible phosphoprotein OA48-18) (cAMP regulatory element-associated protein 1) (CRE-associated protein 1) (CREAP-1)
Gene: LUC7L3

Interactor 2: SRPK3 (Q9UPE1)
SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) (MSSK-1) (Serine/arginine-rich protein-specific kinase 3) (SR-protein-specific kinase 3) (Serine/threonine-protein kinase 23)
Gene: SRPK3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 432 Hs			1 567
+	Hs
		1343079 LUC7L_HUMAN (3-369): 3.35e-51: 178: 32.34		SRPK3_HUMAN (27-567): 5.16e-140: 418: 100.00
+	Hs
		1357641 LC7L2_HUMAN (3-402): 2.11e-47: 168: 28.43		SRPK3_HUMAN (27-567): 5.16e-140: 418: 100.00
+	Hs
		308189 LC7L3_HUMAN (1-432): 1.53e-64: 215: 100.00		SRPK2_HUMAN (297-566): 8.12e-72: 244: 57.69
+	Hs
		308183 LC7L3_HUMAN (1-432): 1.53e-64: 215: 100.00		CLK2_HUMAN (60-227): 1.39e-63: 218: 32.54
+	Hs
		308247 LC7L3_HUMAN (1-432): 1.53e-64: 215: 100.00		SRPK1_HUMAN (368-566): 2.74e-59: 210: 67.84
+	Hs
		942971 LUC7L_HUMAN (3-369): 3.35e-51: 178: 32.34		SRPK2_HUMAN (297-566): 8.12e-72: 244: 57.69
+	Hs
		943032 LC7L2_HUMAN (3-402): 2.11e-47: 168: 28.43		SRPK2_HUMAN (297-566): 8.12e-72: 244: 57.69
+	Hs
		833977 LUC7L_HUMAN (3-369): 3.35e-51: 178: 32.34		CLK2_HUMAN (60-227): 1.39e-63: 218: 32.54
+	Hs
		836108 LC7L2_HUMAN (3-402): 2.11e-47: 168: 28.43		GSK3B_HUMAN (23-336): 1.58e-67: 226: 16.87
+	Hs
		1302060 LUC7L_HUMAN (3-369): 3.35e-51: 178: 32.34		SRPK1_HUMAN (368-566): 2.74e-59: 210: 67.84
+	Hs
		833997 LC7L2_HUMAN (3-402): 2.11e-47: 168: 28.43		CLK2_HUMAN (60-227): 1.39e-63: 218: 32.54
+	Hs
		1302106 LC7L2_HUMAN (3-402): 2.11e-47: 168: 28.43		SRPK1_HUMAN (368-566): 2.74e-59: 210: 67.84
+	At
		1105562 EPN2_ARATH (228-422): 1.08e-32: 133: 16.92		KSG7_ARATH (79-336): 1.55e-72: 238: 16.42
+	Hs
		308182 LC7L3_HUMAN (1-432): 1.53e-64: 215: 100.00		CLK1_HUMAN (405-566): 8.71e-11: 66.2: 26.01
+	Hs
		834127 LUC7L_HUMAN (3-369): 3.35e-51: 178: 32.34		CLK3_HUMAN (396-565): 4.23e-12: 70.9: 25.97
+	Hs
		834152 LC7L2_HUMAN (3-402): 2.11e-47: 168: 28.43		CLK3_HUMAN (396-565): 4.23e-12: 70.9: 25.97