HitPredict

Interactor 1: LC7L3 (O95232)
Luc7-like protein 3 (Cisplatin resistance-associated-overexpressed protein) (Luc7A) (Okadaic acid-inducible phosphoprotein OA48-18) (cAMP regulatory element-associated protein 1) (CRE-associated protein 1) (CREAP-1)
Gene: LUC7L3

Interactor 2: LC7L2 (Q9Y383)
Putative RNA-binding protein Luc7-like 2
Gene: LUC7L2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	26186194, 24981860
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	LUC7~LUC7
Common GO terms	GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0005685 - U1 snRNP GO:0006376 - mRNA splice site recognition GO:0016607 - nuclear speck and 1 others more... GO:0071004 - U2-type prespliceosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 432 Hs			1 392
+	Hs
		308262 LC7L3_HUMAN (1-432): 1.53e-64: 215: 100.00		LUC7L_HUMAN (1-367): 3.39e-77: 244: 66.49
+	Hs
		1343083 LUC7L_HUMAN (3-369): 3.35e-51: 178: 32.34		LC7L2_HUMAN (1-392): 1.49e-78: 249: 100.00
+	Hs
		1343062 LUC7L_HUMAN (3-369): 3.35e-51: 178: 32.34		LUC7L_HUMAN (1-367): 3.39e-77: 244: 66.49
+	Hs
		1377540 LC7L2_HUMAN (3-402): 2.11e-47: 168: 28.43		LC7L2_HUMAN (1-392): 1.49e-78: 249: 100.00
+	Hs
		308147 LC7L3_HUMAN (1-432): 1.53e-64: 215: 100.00		LC7L3_HUMAN (8-389): 5.72e-58: 196: 28.51
+	Sc
		991483 LUC7_YEAST (4-250): 1.36e-56: 189: 25.78		LUC7_YEAST (5-248): 2.16e-65: 210: 30.95
+	Dm
		1376578 Q9W3X8_DROME (1-343): 5.7e-41: 152: 25.56		Q9W3X8_DROME (165-279): 2.1e-18: 88.4: 20.00