HitPredict

Interactor 1: MTMR5 (O95248)
Myotubularin-related protein 5 (Inactive phosphatidylinositol 3-phosphatase 5) (SET-binding factor 1) (Sbf1)
Gene: SBF1

Interactor 2: RHOQ (P17081)
Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) (Ras-like protein family member 7A)
Gene: RHOQ

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DENN~Ras, PH~Ras, Ras~uDENN
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1868 Hs			1 205
+	Hs
		309525 MTMR5_HUMAN (1-1868): 0: 2532: 100.00		RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59
+	Hs
		309470 MTMR5_HUMAN (1-1868): 0: 2532: 100.00		RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97
+	Hs
		309467 MTMR5_HUMAN (1-1868): 0: 2532: 100.00		RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98
+	Hs
		309459 MTMR5_HUMAN (1-1868): 0: 2532: 100.00		CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57
+	Hs
		309460 MTMR5_HUMAN (1-1868): 0: 2532: 100.00		RHOA_HUMAN (1-201): 1.3e-76: 230: 49.75
+	Hs
		309435 MTMR5_HUMAN (1-1868): 0: 2532: 100.00		RAC2_HUMAN (10-196): 1.67e-76: 229: 62.03
+	Hs
		309458 MTMR5_HUMAN (1-1868): 0: 2532: 100.00		RAC3_HUMAN (10-183): 9.1e-76: 227: 66.67
+	Hs
		309466 MTMR5_HUMAN (1-1868): 0: 2532: 100.00		RHOB_HUMAN (1-204): 1.77e-75: 227: 49.51
+	Hs
		309429 MTMR5_HUMAN (1-1868): 0: 2532: 100.00		RHOC_HUMAN (1-192): 1.16e-74: 225: 50.52
+	Hs
		1040888 MTMR1_HUMAN (1097-1647): 3.3e-152: 486: 22.56		RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59
+	Hs
		564518 MTMR1_HUMAN (1097-1647): 3.3e-152: 486: 22.56		RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00
+	Hs
		950979 MTMR1_HUMAN (1097-1647): 3.3e-152: 486: 22.56		RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97
+	Hs
		925261 MTMR1_HUMAN (1097-1647): 3.3e-152: 486: 22.56		RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98
+	Hs
		893983 MTMR1_HUMAN (1097-1647): 3.3e-152: 486: 22.56		CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57
+	Hs
		900451 MTMR1_HUMAN (1097-1647): 3.3e-152: 486: 22.56		RHOA_HUMAN (1-201): 1.3e-76: 230: 49.75
+	Hs
		545361 MTMR1_HUMAN (1097-1647): 3.3e-152: 486: 22.56		RAC2_HUMAN (10-196): 1.67e-76: 229: 62.03
+	Hs
		892358 MTMR1_HUMAN (1097-1647): 3.3e-152: 486: 22.56		RAC3_HUMAN (10-183): 9.1e-76: 227: 66.67
+	Hs
		915659 MTMR1_HUMAN (1097-1647): 3.3e-152: 486: 22.56		RHOB_HUMAN (1-204): 1.77e-75: 227: 49.51
+	Hs
		925348 DEN4C_HUMAN (22-573): 8.87e-127: 443: 21.03		RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98
+	Hs
		915752 DEN2C_HUMAN (3-473): 4.5e-103: 356: 19.96		RHOB_HUMAN (1-204): 1.77e-75: 227: 49.51