HitPredict

Interactor 1: MTMR5 (O95248)
Myotubularin-related protein 5 (Inactive phosphatidylinositol 3-phosphatase 5) (SET-binding factor 1) (Sbf1)
Gene: SBF1

Interactor 2: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DENN~Ras, PH~Ras, Ras~uDENN
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1868 Hs			1 196
+	Hs
		309467 MTMR5_HUMAN (1-1868): 0: 2532: 100.00		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		309460 MTMR5_HUMAN (1-1868): 0: 2532: 100.00		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		309435 MTMR5_HUMAN (1-1868): 0: 2532: 100.00		RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57
+	Hs
		309429 MTMR5_HUMAN (1-1868): 0: 2532: 100.00		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		309470 MTMR5_HUMAN (1-1868): 0: 2532: 100.00		RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53
+	Hs
		309458 MTMR5_HUMAN (1-1868): 0: 2532: 100.00		RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54
+	Hs
		309459 MTMR5_HUMAN (1-1868): 0: 2532: 100.00		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		309438 MTMR5_HUMAN (1-1868): 0: 2532: 100.00		RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74
+	Hs
		120255 MTMR5_HUMAN (1-1868): 0: 2532: 100.00		RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98
+	Hs
		925261 MTMR1_HUMAN (1097-1647): 3.3e-152: 486: 22.56		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		900451 MTMR1_HUMAN (1097-1647): 3.3e-152: 486: 22.56		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		915659 MTMR1_HUMAN (1097-1647): 3.3e-152: 486: 22.56		RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00
+	Hs
		545361 MTMR1_HUMAN (1097-1647): 3.3e-152: 486: 22.56		RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57
+	Hs
		950979 MTMR1_HUMAN (1097-1647): 3.3e-152: 486: 22.56		RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53
+	Hs
		892358 MTMR1_HUMAN (1097-1647): 3.3e-152: 486: 22.56		RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54
+	Hs
		893983 MTMR1_HUMAN (1097-1647): 3.3e-152: 486: 22.56		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		564518 MTMR1_HUMAN (1097-1647): 3.3e-152: 486: 22.56		RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74
+	Hs
		120424 MTMR1_HUMAN (1097-1647): 3.3e-152: 486: 22.56		RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98
+	Hs
		925348 DEN4C_HUMAN (22-573): 8.87e-127: 443: 21.03		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		120487 DEN4C_HUMAN (22-573): 8.87e-127: 443: 21.03		RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98