HitPredict

Interactor 1: MTMR5 (O95248)
Myotubularin-related protein 5 (Inactive phosphatidylinositol 3-phosphatase 5) (SET-binding factor 1) (Sbf1)
Gene: SBF1

Interactor 2: MTMRD (Q86WG5)
Myotubularin-related protein 13 (Inactive phosphatidylinositol 3-phosphatase 13) (SET-binding factor 2)
Gene: SBF2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.64 1.00 0.802

The method score is based on:

Property Details
Experiments 27880917, 25659891
Identification Methods affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DENN~uDENN, GRAM~Myotub-related, Myotub-related~Myotub-related, PH~PH
Common GO terms GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0016020 - membrane
GO:0048471 - perinuclear region of cytoplasm
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 1868
Hs

1 1849
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Last updated: 15 Jul 2024