HitPredict

Interactor 1: MTMR5 (O95248)
Myotubularin-related protein 5 (Inactive phosphatidylinositol 3-phosphatase 5) (SET-binding factor 1) (Sbf1)
Gene: SBF1

Interactor 2: RAB6B (Q9NRW1)
Ras-related protein Rab-6B (EC 3.6.5.2)
Gene: RAB6B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	DENN~Ras, PH~Ras, Ras~uDENN
Common GO terms	GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1868 Hs			1 208
+	Hs
		1040892 MTMR1_HUMAN (1097-1647): 3.3e-152: 486: 22.56		RAB6B_HUMAN (1-208): 4.46e-87: 257: 100.00
+	Hs
		914405 MTMR4_HUMAN (1082-1667): 3.37e-147: 489: 24.11		RB11A_HUMAN (7-206): 6.52e-84: 249: 28.71
+	Hs
		592586 MTMR6_HUMAN (1087-1704): 2.27e-139: 449: 21.47		RAB5A_HUMAN (3-207): 4.67e-89: 262: 40.78
+	Hs
		592309 DEN4C_HUMAN (22-573): 8.87e-127: 443: 21.03		RAB5A_HUMAN (3-207): 4.67e-89: 262: 40.78
+	Hs
		914171 MYCPP_HUMAN (22-564): 1.54e-130: 454: 21.99		RB11A_HUMAN (7-206): 6.52e-84: 249: 28.71
+	Hs
		914468 MTMR6_HUMAN (1087-1704): 2.27e-139: 449: 21.47		RB11A_HUMAN (7-206): 6.52e-84: 249: 28.71
+	Hs
		914128 DEN4C_HUMAN (22-573): 8.87e-127: 443: 21.03		RB11A_HUMAN (7-206): 6.52e-84: 249: 28.71
+	Dm
		183448 CRAG_DROME (22-539): 4.36e-109: 387: 22.04		O15971_DROME (14-207): 6e-89: 261: 39.18
+	Hs
		914156 DEN5B_HUMAN (3-354): 1.58e-102: 362: 24.69		RB11A_HUMAN (7-206): 6.52e-84: 249: 28.71
+	Mm
		722738 DEN5A_MOUSE (2-365): 8.28e-98: 348: 24.43		RAB6A_MOUSE (1-208): 9.38e-85: 251: 90.87
+	Hs
		895124 DEN4C_HUMAN (22-573): 8.87e-127: 443: 21.03		RAB2A_HUMAN (14-191): 5.16e-45: 150: 39.89