HitPredict

Interactor 1: GOSR1 (O95249)
Golgi SNAP receptor complex member 1 (28 kDa Golgi SNARE protein) (28 kDa cis-Golgi SNARE p28) (GOS-28)
Gene: GOSR1

Interactor 2: STX12 (Q86Y82)
Syntaxin-12
Gene: STX12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.847

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	SNARE~V-SNARE_C
Common GO terms	GO:0000139 - Golgi membrane GO:0005484 - SNAP receptor activity GO:0005794 - Golgi apparatus GO:0006906 - vesicle fusion GO:0031201 - SNARE complex
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 250 Hs			1 276
+	Hs
		92395 E9PCW1_HUMAN (1-250): 5.28e-111: 320: 99.20		STX12_HUMAN (1-257): 2.32e-67: 212: 100.00
+	Hs
		178342 GOSR1_HUMAN (1-250): 6.41e-114: 328: 100.00		STX7_HUMAN (8-272): 1.12e-55: 181: 51.70
+	Hs
		309582 GOSR1_HUMAN (1-250): 6.41e-114: 328: 100.00		STX3_HUMAN (5-250): 2.56e-53: 176: 25.20
+	Hs
		92384 E9PCW1_HUMAN (1-250): 5.28e-111: 320: 99.20		STX7_HUMAN (8-272): 1.12e-55: 181: 51.70
+	Hs
		92391 E9PCW1_HUMAN (1-250): 5.28e-111: 320: 99.20		STX3_HUMAN (5-250): 2.56e-53: 176: 25.20
+	Dm
		1098098 GOSR1_DROME (5-250): 8.4e-72: 221: 45.75		STX1A_DROME (4-273): 6.4e-64: 204: 22.10
+	Dm
		1178784 GOSR1_DROME (5-250): 8.4e-72: 221: 45.75		Q7K0X9_DROME (21-274): 3.74e-54: 178: 31.84
+	Dm
		1364301 GOSR1_DROME (5-250): 8.4e-72: 221: 45.75		Q9VU45_DROME (13-269): 2.95e-49: 166: 28.41
+	Sc
		699196 GOSR1_YEAST (36-246): 6.41e-56: 180: 24.06		PEP12_YEAST (30-249): 1.29e-11: 65.5: 25.64