HitPredict

Interactor 1: KAT7 (O95251)
Histone acetyltransferase KAT7 (EC 2.3.1.48) (Histone acetyltransferase binding to ORC1) (Lysine acetyltransferase 7) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (MYST-2)
Gene: KAT7

Interactor 2: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	29467282, 30415952, 36424410
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 611 Hs			1 454
+	Hs
		347907 KAT8_HUMAN (242-609): 1.43e-177: 512: 48.11		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		347509 KAT5_HUMAN (325-607): 2.87e-149: 442: 53.82		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Mm
		348441 KAT5_MOUSE (325-607): 5.61e-149: 441: 53.82		MYC_MOUSE (1-454): 4.33e-119: 357: 89.01
+	Hs
		379684 KAT5_HUMAN (325-607): 2.87e-149: 442: 53.82		MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40
+	Hs
		519726 KAT5_HUMAN (325-607): 2.87e-149: 442: 53.82		MYCL_HUMAN (29-449): 4.2e-42: 154: 30.11
+	Mm
		659351 KAT5_MOUSE (325-607): 5.61e-149: 441: 53.82		MAX_MOUSE (354-454): 3.52e-25: 102: 32.67
+	Hs
		898167 KAT5_HUMAN (325-607): 2.87e-149: 442: 53.82		MAX_HUMAN (354-454): 1.39e-24: 101: 32.67