HitPredict

Interactor 1: KAT7 (O95251)
Histone acetyltransferase KAT7 (EC 2.3.1.48) (Histone acetyltransferase binding to ORC1) (Lysine acetyltransferase 7) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (MYST-2)
Gene: KAT7

Interactor 2: BRD2 (P25440)
Bromodomain-containing protein 2 (O27.1.1)
Gene: BRD2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30554943
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 611 Hs			1 801
+	Hs
		309702 KAT7_HUMAN (1-611): 0: 1035: 100.00		BRD3_HUMAN (53-764): 4.91e-124: 390: 56.56
+	Hs
		243738 KAT7_HUMAN (1-611): 0: 1035: 100.00		BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89
+	Hs
		309639 KAT7_HUMAN (1-611): 0: 1035: 100.00		BRD1_HUMAN (54-330): 3.85e-29: 127: 17.79
+	Hs
		309749 KAT7_HUMAN (1-611): 0: 1035: 100.00		BRD7_HUMAN (25-338): 4.42e-29: 125: 17.13
+	Hs
		309758 KAT7_HUMAN (1-611): 0: 1035: 100.00		BRPF3_HUMAN (8-510): 5.66e-28: 123: 15.88
+	Hs
		309660 KAT7_HUMAN (1-611): 0: 1035: 100.00		TAF1_HUMAN (64-263): 1.16e-16: 87.2: 16.00
+	Hs
		244948 KAT8_HUMAN (242-609): 1.43e-177: 512: 48.11		BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89
+	Hs
		244747 KAT5_HUMAN (325-607): 2.87e-149: 442: 53.82		BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89
+	Hs
		998941 KAT6A_HUMAN (251-607): 1.15e-146: 469: 50.28		EP300_HUMAN (31-183): 5.52e-39: 159: 30.72
+	Hs
		998954 KAT5_HUMAN (325-607): 2.87e-149: 442: 53.82		EP300_HUMAN (31-183): 5.52e-39: 159: 30.72
+	Hs
		319291 KAT6A_HUMAN (251-607): 1.15e-146: 469: 50.28		BRD1_HUMAN (54-330): 3.85e-29: 127: 17.79
+	Hs
		1270980 KAT6A_HUMAN (251-607): 1.15e-146: 469: 50.28		BRPF3_HUMAN (8-510): 5.66e-28: 123: 15.88
+	Hs
		319284 KAT6B_HUMAN (299-607): 1.97e-143: 460: 55.99		BRD1_HUMAN (54-330): 3.85e-29: 127: 17.79
+	Hs
		1264463 KAT6B_HUMAN (299-607): 1.97e-143: 460: 55.99		BRPF3_HUMAN (8-510): 5.66e-28: 123: 15.88
+	Hs
		319294 KAT5_HUMAN (325-607): 2.87e-149: 442: 53.82		BRD1_HUMAN (54-330): 3.85e-29: 127: 17.79
+	Hs
		1199175 KAT6A_HUMAN (251-607): 1.15e-146: 469: 50.28		PB1_HUMAN (306-773): 2.79e-18: 92.6: 12.33
+	Sc
		991242 ESA1_YEAST (291-611): 1.11e-152: 448: 46.79		BDF2_YEAST (352-546): 6.82e-22: 103: 22.22
+	Sc
		728774 ESA1_YEAST (291-611): 1.11e-152: 448: 46.79		BDF1_YEAST (16-240): 5.3e-20: 97.2: 22.47
+	Hs
		1273483 KAT5_HUMAN (325-607): 2.87e-149: 442: 53.82		BRD8_HUMAN (79-206): 5.14e-18: 91.5: 20.31
+	Dm
		137465 MOF_DROME (272-610): 1.29e-146: 446: 42.40		NU301_DROME (84-177): 1.14e-11: 70.9: 39.36