HitPredict

Interactor 1: I18RA (O95256)
Interleukin-18 receptor accessory protein (IL-18 receptor accessory protein) (IL-18RAcP) (EC 3.2.2.6) (Accessory protein-like) (AcPL) (CD218 antigen-like family member B) (CDw218b) (IL-1R accessory protein-like) (IL-1RAcPL) (Interleukin-1 receptor 7) (IL-1R-7) (IL-1R7) (Interleukin-18 receptor accessory protein-like) (Interleukin-18 receptor beta) (IL-18R-beta) (IL-18Rbeta) (CD antigen CD218b)
Gene: IL18RAP

Interactor 2: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	18003981
Identification Methods	pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0006954 - inflammatory response
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 599 Hs			1 192
+	Hs
		540389 IL1R1_HUMAN (71-588): 3.2e-84: 275: 22.14		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Hs
		925644 IL1AP_HUMAN (59-576): 1.09e-74: 250: 22.16		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Hs
		436525 IL1AP_HUMAN (59-576): 1.09e-74: 250: 22.16		RHOC_HUMAN (5-192): 8.68e-75: 224: 57.45
+	Hs
		925776 ROBO1_HUMAN (50-488): 2.04e-58: 214: 11.01		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Hs
		564764 ROBO1_HUMAN (50-488): 2.04e-58: 214: 11.01		RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67
+	Hs
		894276 PXDN_HUMAN (8-485): 5.96e-64: 230: 14.06		CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31
+	Hs
		1331019 ROBO1_HUMAN (50-488): 2.04e-58: 214: 11.01		RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64
+	Hs
		894644 ROBO1_HUMAN (50-488): 2.04e-58: 214: 11.01		CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31
+	Hs
		901110 ROBO1_HUMAN (50-488): 2.04e-58: 214: 11.01		RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98
+	Hs
		436602 ROBO1_HUMAN (50-488): 2.04e-58: 214: 11.01		RHOC_HUMAN (5-192): 8.68e-75: 224: 57.45
+	Hs
		452386 PGFRB_HUMAN (52-472): 3.21e-13: 75.1: 10.93		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Hs
		452341 PGFRB_HUMAN (52-472): 3.21e-13: 75.1: 10.93		RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19
+	Hs
		894044 MYLK_HUMAN (145-239): 2.43e-10: 65.8: 13.33		CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31