Interactor 1: TNKS1 (O95271)
Poly [ADP-ribose] polymerase tankyrase-1 (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 5) (ARTD5) (Poly [ADP-ribose] polymerase 5A) (Protein poly-ADP-ribosyltransferase tankyrase-1) (EC 2.4.2.-) (TNKS-1) (TRF1-interacting ankyrin-related ADP-ribose polymerase) (Tankyrase I) (Tankyrase-1) (TANK1)
Gene: TNKS

Interactor 2: TERF1 (P54274)
Telomeric repeat-binding factor 1 (NIMA-interacting protein 2) (TTAGGG repeat-binding factor 1) (Telomeric protein Pin2/TRF1)
Gene: TERF1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 0.60 0.765

The method score is based on:

Property Details
Experiments 26186194, 26496610, 28514442, 11739745, 11854288, 12080061, 9822378, 33961781, 11802774, 20811636, 22645305, 23583392, 15133513, 36383218, 10988299, 20696165
Identification Methods affinity chromatography technology, two hybrid, pull down, enzymatic study, biochemical, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000781 - chromosome, telomeric region
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0016604 - nuclear body
and 2 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 1327
Hs

1 439
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024