HitPredict

Interactor 1: TNKS1 (O95271)
Poly [ADP-ribose] polymerase tankyrase-1 (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 5) (ARTD5) (Poly [ADP-ribose] polymerase 5A) (Protein poly-ADP-ribosyltransferase tankyrase-1) (EC 2.4.2.-) (TNKS-1) (TRF1-interacting ankyrin-related ADP-ribose polymerase) (Tankyrase I) (Tankyrase-1) (TANK1)
Gene: TNKS

Interactor 2: AP2M1 (Q96CW1)
AP-2 complex subunit mu (AP-2 mu chain) (Adaptin-mu2) (Adaptor protein complex AP-2 subunit mu) (Adaptor-related protein complex 2 subunit mu) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (HA2 50 kDa subunit) (Plasma membrane adaptor AP-2 50 kDa protein)
Gene: AP2M1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 1327 Hs			1 435
+	Hs
		166993 ANR28_HUMAN (39-924): 1.84e-160: 511: 22.33		AP2M1_HUMAN (1-435): 1.03e-178: 507: 100.00
+	Hs
		1239494 ANR52_HUMAN (906-1267): 2.51e-21: 103: 12.88		AP2M1_HUMAN (1-435): 1.03e-178: 507: 100.00
+	Hs
		1287489 TNKS2_HUMAN (39-198): 1.68e-13: 77.6: 9.38		AP2M1_HUMAN (1-435): 1.03e-178: 507: 100.00