Interactor 1: EPM2A (O95278)
Laforin (EC 3.1.3.-) (EC 3.1.3.16) (EC 3.1.3.48) (Glucan phosphatase) (Glycogen phosphatase) (Lafora PTPase) (LAFPTPase)
Gene: EPM2A

Interactor 2: NHLC1 (Q6VVB1)
E3 ubiquitin-protein ligase NHLRC1 (EC 2.3.2.27) (Malin) (NHL repeat-containing protein 1) (RING-type E3 ubiquitin transferase NHLRC1)
Gene: NHLRC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 0.60 0.763

The method score is based on:

Property Details
Experiments 22578008, 26648032, 31758957, 33961781, 36638890, 16115820, 15930137, 18617530, 26546463, 30041081, 18029386, 21505799, 23922729
Identification Methods pull down, affinity chromatography technology, two hybrid, enzymatic study, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0005978 - glycogen biosynthetic process
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
and 1 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 331
Hs

1 395
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024