HitPredict - High confidence protein-protein interactions

Interactor 1: VAPB (O95292)
Vesicle-associated membrane protein-associated protein B/C (VAMP-B/VAMP-C) (VAMP-associated protein B/C) (VAP-B/VAP-C)
Gene: VAPB

Interactor 2: VAPB (O95292)
Vesicle-associated membrane protein-associated protein B/C (VAMP-B/VAMP-C) (VAMP-associated protein B/C) (VAP-B/VAP-C)
Gene: VAPB

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	34948065, 16227268
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Motile_Sperm~Motile_Sperm
Common GO terms	GO:0005737 - cytoplasm GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0005794 - Golgi apparatus GO:0005886 - plasma membrane and 23 others more... GO:0006874 - intracellular calcium ion homeostasis GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport GO:0007029 - endoplasmic reticulum organization GO:0008017 - microtubule binding GO:0019076 - viral release from host cell GO:0019899 - enzyme binding GO:0030301 - cholesterol transport GO:0030968 - endoplasmic reticulum unfolded protein response GO:0033149 - FFAT motif binding GO:0036498 - IRE1-mediated unfolded protein response GO:0042803 - protein homodimerization activity GO:0044790 - suppression of viral release by host GO:0044828 - negative regulation by host of viral genome replication GO:0044829 - positive regulation by host of viral genome replication GO:0044830 - modulation by host of viral RNA genome replication GO:0045070 - positive regulation of viral genome replication GO:0045296 - cadherin binding GO:0046725 - negative regulation by virus of viral protein levels in host cell GO:0046982 - protein heterodimerization activity GO:0048487 - beta-tubulin binding GO:0061817 - endoplasmic reticulum-plasma membrane tethering GO:0090114 - COPII-coated vesicle budding GO:0090158 - endoplasmic reticulum membrane organization
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1	243
Hs

1	243

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Last updated: 15 Jul 2024