HitPredict

Interactor 1: VAPB (O95292)
Vesicle-associated membrane protein-associated protein B/C (VAMP-B/VAMP-C) (VAMP-associated protein B/C) (VAP-B/VAP-C)
Gene: VAPB

Interactor 2: FGFR1 (P11362)
Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)
Gene: FGFR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0042803 - protein homodimerization activity
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 243 Hs			1 822
+	Hs
		508237 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		FGFR1_HUMAN (1-822): 0: 861: 100.00
+	Hs
		310508 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		FGFR3_HUMAN (6-821): 0: 730: 61.22
+	Hs
		310517 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		EPHA3_HUMAN (3-775): 0: 643: 19.03
+	Hs
		310571 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		EPHA5_HUMAN (3-791): 0: 639: 19.15
+	Hs
		665437 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		EPHA3_HUMAN (3-775): 0: 643: 19.03
+	Hs
		310518 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		EPHA8_HUMAN (3-819): 0: 603: 19.35
+	Hs
		665538 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		EPHA8_HUMAN (3-819): 0: 603: 19.35
+	Hs
		310655 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		NTRK2_HUMAN (102-762): 5.62e-163: 495: 22.70
+	Hs
		310653 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		NTRK3_HUMAN (163-762): 3.3e-161: 491: 25.08
+	Hs
		310520 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		UFO_HUMAN (8-815): 1.07e-155: 479: 21.98
+	Hs
		1081631 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		NTRK3_HUMAN (163-762): 3.3e-161: 491: 25.08
+	Hs
		310462 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		NTRK1_HUMAN (122-769): 8.92e-140: 434: 25.96
+	Hs
		385634 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		NTRK1_HUMAN (122-769): 8.92e-140: 434: 25.96
+	Hs
		310470 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		RET_HUMAN (384-774): 2.63e-98: 332: 45.77
+	Hs
		434298 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		RET_HUMAN (384-774): 2.63e-98: 332: 45.77
+	Hs
		434244 MSPD2_HUMAN (4-182): 2.15e-38: 141: 25.41		RET_HUMAN (384-774): 2.63e-98: 332: 45.77
+	Hs
		310529 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		VGFR3_HUMAN (31-128): 2.94e-10: 66.3: 21.15