HitPredict

Interactor 1: VAPB (O95292)
Vesicle-associated membrane protein-associated protein B/C (VAMP-B/VAMP-C) (VAMP-associated protein B/C) (VAP-B/VAP-C)
Gene: VAPB

Interactor 2: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 243 Hs			1 245
+	Hs
		310586 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Hs
		310595 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		310523 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Hs
		910105 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Hs
		647335 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		927599 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		683768 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Hs
		310610 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		1433F_HUMAN (2-242): 7.16e-106: 307: 71.43
+	Hs
		310585 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33
+	Zm
		19785 A0A1D6HF60_MAIZE (2-190): 1.27e-44: 161: 27.45		B6U284_MAIZE (1-243): 2.35e-143: 403: 59.92
+	Zm
		19784 A0A1D6HF60_MAIZE (2-190): 1.27e-44: 161: 27.45		B6SRI4_MAIZE (1-243): 5.53e-143: 401: 59.92
+	Hs
		982562 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		1433F_HUMAN (2-242): 7.16e-106: 307: 71.43
+	Mm
		935710 VAPA_MOUSE (1-243): 6.07e-79: 239: 62.30		1433F_MOUSE (2-242): 4.62e-106: 308: 71.43
+	Hs
		905194 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33