HitPredict

Interactor 1: VAPB (O95292)
Vesicle-associated membrane protein-associated protein B/C (VAMP-B/VAMP-C) (VAMP-associated protein B/C) (VAP-B/VAP-C)
Gene: VAPB

Interactor 2: CALX (P27824)
Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90)
Gene: CANX

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	29568061, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 243 Hs			1 592
+	Hs
		654860 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		654575 MSPD2_HUMAN (4-182): 2.15e-38: 141: 25.41		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		310515 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		CALR_HUMAN (67-470): 1.19e-141: 418: 38.33
+	Hs
		653756 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		CALR_HUMAN (67-470): 1.19e-141: 418: 38.33