HitPredict

Interactor 1: VAPB (O95292)
Vesicle-associated membrane protein-associated protein B/C (VAMP-B/VAMP-C) (VAMP-associated protein B/C) (VAP-B/VAP-C)
Gene: VAPB

Interactor 2: EPHA3 (P29320)
Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) (hEK4) (HEK) (Human embryo kinase) (Tyrosine-protein kinase TYRO4) (Tyrosine-protein kinase receptor ETK1) (Eph-like tyrosine kinase 1)
Gene: EPHA3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 243 Hs			1 983
+	Hs
		665437 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		EPHA3_HUMAN (1-983): 0: 1248: 100.00
+	Hs
		310571 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		EPHA5_HUMAN (7-983): 0: 1202: 65.97
+	Hs
		310518 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		EPHA8_HUMAN (29-982): 0: 1099: 56.57
+	Hs
		665538 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		EPHA8_HUMAN (29-982): 0: 1099: 56.57
+	Hs
		310520 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		UFO_HUMAN (265-962): 1.06e-153: 479: 22.82
+	Hs
		310490 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		INSRR_HUMAN (295-918): 5.63e-141: 455: 24.85
+	Hs
		310471 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		IGF1R_HUMAN (366-883): 1.6e-139: 453: 30.02
+	Hs
		310468 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		INSR_HUMAN (375-880): 6.57e-136: 444: 30.32
+	Hs
		435786 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		IGF1R_HUMAN (366-883): 1.6e-139: 453: 30.02
+	Hs
		411513 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		INSR_HUMAN (375-880): 6.57e-136: 444: 30.32
+	Ce
		219681 O44782_CAEEL (1-242): 1.51e-69: 215: 34.01		VAB1_CAEEL (574-956): 2.3e-101: 344: 41.53