HitPredict

Interactor 1: VAPB (O95292)
Vesicle-associated membrane protein-associated protein B/C (VAMP-B/VAMP-C) (VAMP-associated protein B/C) (VAP-B/VAP-C)
Gene: VAPB

Interactor 2: KAP1 (P31321)
cAMP-dependent protein kinase type I-beta regulatory subunit
Gene: PRKAR1B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 243 Hs			1 381
+	Hs
		679319 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		KAP1_HUMAN (1-381): 6.21e-138: 399: 100.00
+	Hs
		310478 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		KAP0_HUMAN (1-381): 7.91e-129: 376: 81.37
+	Mm
		522393 VAPA_MOUSE (1-243): 6.07e-79: 239: 62.30		KAP1_MOUSE (1-381): 5.32e-137: 397: 94.75
+	Hs
		498364 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		KAP0_HUMAN (1-381): 7.91e-129: 376: 81.37
+	Zm
		19782 A0A1D6HF60_MAIZE (2-190): 1.27e-44: 161: 27.45		A0A1D6QNV1_MAIZE (35-380): 4.1e-59: 208: 23.08
+	Hs
		310522 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		KAP3_HUMAN (233-379): 1.57e-18: 88.2: 26.53