HitPredict

Interactor 1: VAPB (O95292)
Vesicle-associated membrane protein-associated protein B/C (VAMP-B/VAMP-C) (VAMP-associated protein B/C) (VAP-B/VAP-C)
Gene: VAPB

Interactor 2: STX2 (P32856)
Syntaxin-2 (Epimorphin)
Gene: STX2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	12651853
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 243 Hs			1 288
+	Mm
		898821 Q8BH80_MOUSE (1-243): 1.1e-89: 266: 90.12		STX1B_MOUSE (1-287): 6.03e-81: 247: 64.81
+	Hs
		310582 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		STX1B_HUMAN (1-287): 6.03e-81: 247: 64.81
+	Mm
		192853 Q8BH80_MOUSE (1-243): 1.1e-89: 266: 90.12		STX1A_MOUSE (1-287): 5.2e-78: 240: 65.63
+	Hs
		310656 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		STX1A_HUMAN (1-286): 4.14e-76: 235: 64.46
+	Hs
		1084002 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		STX1A_HUMAN (1-286): 4.14e-76: 235: 64.46
+	Hs
		310616 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		STX4_HUMAN (1-286): 1.23e-60: 196: 42.57
+	Hs
		310621 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		STX3_HUMAN (1-287): 6.25e-60: 194: 63.79
+	Hs
		1017830 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		STX4_HUMAN (1-286): 1.23e-60: 196: 42.57
+	Hs
		178343 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		STX7_HUMAN (36-284): 1.29e-48: 164: 27.78
+	Hs
		178823 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		STX7_HUMAN (36-284): 1.29e-48: 164: 27.78
+	At
		1258324 VAP11_ARATH (3-194): 1.3e-60: 193: 25.71		SY132_ARATH (7-267): 1.34e-50: 170: 24.35
+	At
		1258341 VAP11_ARATH (3-194): 1.3e-60: 193: 25.71		SYP31_ARATH (2-283): 1.3e-45: 158: 13.95
+	At
		1258071 VAP42_ARATH (8-186): 5.77e-48: 161: 20.65		SY121_ARATH (17-265): 1.97e-54: 181: 22.96
+	At
		1258067 VAP42_ARATH (8-186): 5.77e-48: 161: 20.65		SYP43_ARATH (11-283): 1.75e-53: 178: 18.55
+	At
		1258065 VAP42_ARATH (8-186): 5.77e-48: 161: 20.65		SY132_ARATH (7-267): 1.34e-50: 170: 24.35
+	At
		1258069 VAP42_ARATH (8-186): 5.77e-48: 161: 20.65		SYP42_ARATH (15-283): 2.42e-50: 170: 20.37
+	At
		1258068 VAP42_ARATH (8-186): 5.77e-48: 161: 20.65		SY122_ARATH (26-265): 1.21e-49: 169: 24.19
+	At
		1258070 VAP42_ARATH (8-186): 5.77e-48: 161: 20.65		SY123_ARATH (4-266): 3.49e-50: 169: 25.09
+	At
		955669 VAP42_ARATH (8-186): 5.77e-48: 161: 20.65		SYP22_ARATH (15-271): 7.05e-48: 162: 18.66
+	At
		955662 VAP41_ARATH (11-186): 1.31e-44: 152: 21.43		SYP22_ARATH (15-271): 7.05e-48: 162: 18.66