HitPredict

Interactor 1: VAPB (O95292)
Vesicle-associated membrane protein-associated protein B/C (VAMP-B/VAMP-C) (VAMP-associated protein B/C) (VAP-B/VAP-C)
Gene: VAPB

Interactor 2: VGFR3 (P35916)
Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like tyrosine kinase 4) (FLT-4) (Tyrosine-protein kinase receptor FLT4)
Gene: FLT4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0042803 - protein homodimerization activity
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 243 Hs			1 1363
+	Hs
		310571 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		EPHA5_HUMAN (373-1199): 1.28e-153: 493: 13.44
+	Hs
		310517 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		EPHA3_HUMAN (386-1200): 1.47e-152: 489: 14.15
+	Hs
		665437 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		EPHA3_HUMAN (386-1200): 1.47e-152: 489: 14.15
+	Hs
		310474 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		PGFRB_HUMAN (19-555): 1.14e-123: 413: 22.80
+	Hs
		310470 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		RET_HUMAN (801-1176): 1.25e-74: 273: 40.63
+	Hs
		434298 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		RET_HUMAN (801-1176): 1.25e-74: 273: 40.63
+	Hs
		310494 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		PGFRA_HUMAN (11-549): 8.68e-55: 211: 20.36
+	Hs
		557271 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		PGFRA_HUMAN (11-549): 8.68e-55: 211: 20.36
+	Hs
		434244 MSPD2_HUMAN (4-182): 2.15e-38: 141: 25.41		RET_HUMAN (801-1176): 1.25e-74: 273: 40.63
+	Hs
		310508 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		FGFR3_HUMAN (310-670): 4.9e-27: 121: 13.53
+	Hs
		169155 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		MUSK_HUMAN (2-152): 6.12e-16: 85.4: 13.25
+	Hs
		310482 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		FGFR1_HUMAN (2-160): 6.17e-14: 78.9: 11.93
+	Hs
		169211 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		MUSK_HUMAN (2-152): 6.12e-16: 85.4: 13.25
+	Hs
		310652 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		SPEG_HUMAN (667-890): 8.26e-10: 66.2: 19.82
+	Hs
		508237 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		FGFR1_HUMAN (2-160): 6.17e-14: 78.9: 11.93