HitPredict

Interactor 1: VAPB (O95292)
Vesicle-associated membrane protein-associated protein B/C (VAMP-B/VAMP-C) (VAMP-associated protein B/C) (VAP-B/VAP-C)
Gene: VAPB

Interactor 2: ROR1 (Q01973)
Inactive tyrosine-protein kinase transmembrane receptor ROR1 (Neurotrophic tyrosine kinase, receptor-related 1)
Gene: ROR1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34948065
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 243 Hs			1 937
+	Hs
		310606 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		ROR2_HUMAN (1-936): 0: 665: 55.33
+	Hs
		968502 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		ROR2_HUMAN (1-936): 0: 665: 55.33
+	Hs
		169155 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		MUSK_HUMAN (30-758): 2.24e-169: 517: 26.91
+	Hs
		169211 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		MUSK_HUMAN (30-758): 2.24e-169: 517: 26.91
+	Hs
		310508 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		FGFR3_HUMAN (12-806): 3.86e-160: 491: 19.69
+	Hs
		310482 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		FGFR1_HUMAN (19-798): 2.01e-155: 480: 17.93
+	Hs
		508237 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		FGFR1_HUMAN (19-798): 2.01e-155: 480: 17.93
+	Hs
		310520 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		UFO_HUMAN (40-830): 6.99e-147: 459: 18.51
+	Hs
		310470 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		RET_HUMAN (170-849): 1.43e-143: 457: 22.46
+	Hs
		434298 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		RET_HUMAN (170-849): 1.43e-143: 457: 22.46
+	Hs
		310655 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		NTRK2_HUMAN (435-754): 9.13e-115: 372: 41.75
+	Hs
		310462 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		NTRK1_HUMAN (478-748): 5.71e-72: 255: 46.89
+	Hs
		310653 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		NTRK3_HUMAN (438-743): 2.52e-67: 243: 40.50
+	Hs
		385634 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		NTRK1_HUMAN (478-748): 5.71e-72: 255: 46.89
+	Hs
		1081631 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		NTRK3_HUMAN (438-743): 2.52e-67: 243: 40.50
+	Hs
		310658 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		DDR2_HUMAN (466-746): 6.8e-58: 216: 39.87
+	Hs
		310490 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		INSRR_HUMAN (467-742): 1.32e-55: 211: 39.35
+	Hs
		310471 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		IGF1R_HUMAN (467-742): 3.41e-54: 207: 39.71
+	Hs
		310863 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		ALK_HUMAN (404-746): 1.74e-53: 205: 35.20
+	Hs
		435786 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		IGF1R_HUMAN (467-742): 3.41e-54: 207: 39.71