HitPredict

Interactor 1: VAPB (O95292)
Vesicle-associated membrane protein-associated protein B/C (VAMP-B/VAMP-C) (VAMP-associated protein B/C) (VAP-B/VAP-C)
Gene: VAPB

Interactor 2: CKAP4 (Q07065)
Cytoskeleton-associated protein 4 (63-kDa cytoskeleton-linking membrane protein) (Climp-63) (p63)
Gene: CKAP4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	34079125, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0005886 - plasma membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 243 Hs			1 602
+	Hs
		990721 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		CKAP4_HUMAN (1-602): 2e-38: 151: 100.00
+	Hs
		310734 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		RBCC1_HUMAN (159-601): 1.73e-09: 63.3: 17.47
+	Hs
		502880 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		LAMC1_HUMAN (304-590): 1.27e-11: 70: 12.71
+	Hs
		1255711 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		RBCC1_HUMAN (159-601): 1.73e-09: 63.3: 17.47
+	Hs
		1189777 MSPD2_HUMAN (4-182): 2.15e-38: 141: 25.41		MYH14_HUMAN (127-597): 5.01e-26: 116: 13.49