HitPredict

Interactor 1: VAPB (O95292)
Vesicle-associated membrane protein-associated protein B/C (VAMP-B/VAMP-C) (VAMP-associated protein B/C) (VAP-B/VAP-C)
Gene: VAPB

Interactor 2: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62)
Gene: SQSTM1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	34948065, 33545068
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005783 - endoplasmic reticulum GO:0019899 - enzyme binding
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 243 Hs			1 440
+	Hs
		1036958 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		SQSTM_HUMAN (1-440): 0: 760: 100.00
+	Hs
		310632 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		NBR1_HUMAN (80-184): 5.95e-10: 63.6: 24.78
+	Hs
		1056152 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		NBR1_HUMAN (80-184): 5.95e-10: 63.6: 24.78