HitPredict

Interactor 1: VAPB (O95292)
Vesicle-associated membrane protein-associated protein B/C (VAMP-B/VAMP-C) (VAMP-associated protein B/C) (VAP-B/VAP-C)
Gene: VAPB

Interactor 2: KCNB1 (Q14721)
Potassium voltage-gated channel subfamily B member 1 (Delayed rectifier potassium channel 1) (DRK1) (h-DRK1) (Voltage-gated potassium channel subunit Kv2.1)
Gene: KCNB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	29941597
Identification Methods	fluorescent resonance energy transfer
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0046982 - protein heterodimerization activity
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 243 Hs			1 858
+	Mm
		977387 Q8BH80_MOUSE (1-243): 1.1e-89: 266: 90.12		KCNB1_MOUSE (1-858): 0: 712: 93.71
+	Hs
		1058648 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		KCNB1_HUMAN (1-858): 0: 725: 100.00
+	Mm
		977393 VAPA_MOUSE (1-243): 6.07e-79: 239: 62.30		KCNB1_MOUSE (1-858): 0: 712: 93.71
+	Hs
		1273160 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		KCNB2_HUMAN (2-858): 0: 640: 60.68
+	Hs
		310507 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		KCNA4_HUMAN (5-506): 1.1e-123: 389: 32.22
+	Hs
		608253 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		KCNA4_HUMAN (5-506): 1.1e-123: 389: 32.22