HitPredict

Interactor 1: VAPB (O95292)
Vesicle-associated membrane protein-associated protein B/C (VAMP-B/VAMP-C) (VAMP-associated protein B/C) (VAP-B/VAP-C)
Gene: VAPB

Interactor 2: MPRIP (Q6WCQ1)
Myosin phosphatase Rho-interacting protein (M-RIP) (Rho-interacting protein 3) (RIP3) (p116Rip)
Gene: MPRIP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045296 - cadherin binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 243 Hs			1 1025
+	Hs
		1167437 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		MPRIP_HUMAN (1-1025): 9.29e-127: 412: 100.00
+	Hs
		310806 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		TARA_HUMAN (231-985): 1.44e-51: 201: 35.57
+	Hs
		1329251 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		TARA_HUMAN (231-985): 1.44e-51: 201: 35.57
+	Hs
		310745 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		OSBP2_HUMAN (273-623): 1.26e-32: 138: 15.11
+	Hs
		1282120 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		OSBP2_HUMAN (273-623): 1.26e-32: 138: 15.11
+	Hs
		1189777 MSPD2_HUMAN (4-182): 2.15e-38: 141: 25.41		MYH14_HUMAN (595-972): 3.69e-09: 63.1: 14.89