HitPredict

Interactor 1: VAPB (O95292)
Vesicle-associated membrane protein-associated protein B/C (VAMP-B/VAMP-C) (VAMP-associated protein B/C) (VAP-B/VAP-C)
Gene: VAPB

Interactor 2: M4K3 (Q8IVH8)
Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal center kinase-related protein kinase) (GLK) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3)
Gene: MAP4K3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 243 Hs			1 894
+	Hs
		310617 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		STK4_HUMAN (10-288): 2.22e-119: 373: 46.43
+	Hs
		310619 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		STK3_HUMAN (10-288): 2.29e-117: 368: 45.36
+	Hs
		1023129 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		STK4_HUMAN (10-288): 2.22e-119: 373: 46.43
+	Hs
		1027447 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		STK3_HUMAN (10-288): 2.29e-117: 368: 45.36