Interactor 1: VAPB (O95292)
Vesicle-associated membrane protein-associated protein B/C (VAMP-B/VAMP-C) (VAMP-associated protein B/C) (VAP-B/VAP-C)
Gene: VAPB

Interactor 2: VAPA (Q9P0L0)
Vesicle-associated membrane protein-associated protein A (VAMP-A) (VAMP-associated protein A) (VAP-A) (33 kDa VAMP-associated protein) (VAP-33)
Gene: VAPA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.977

The method score is based on:

Property Details
Experiments 26186194, 33961781, 35271311, 26496610, 28514442, 9920726, 34079125, 34349018, 35235311, 19515777, 16227268
Identification Methods affinity chromatography technology, pull down, proximity labelling technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Motile_Sperm~Motile_Sperm
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0005886 - plasma membrane
GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport
GO:0008017 - microtubule binding
and 10 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 243
Hs

1 249
+ Hs
+ Rn
+ Hs
+ Zm
+ Zm
+ At
+ Hs
+ Sc
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024