HitPredict

Interactor 1: VAPB (O95292)
Vesicle-associated membrane protein-associated protein B/C (VAMP-B/VAMP-C) (VAMP-associated protein B/C) (VAP-B/VAP-C)
Gene: VAPB

Interactor 2: SEC63 (Q9UGP8)
Translocation protein SEC63 homolog (DnaJ homolog subfamily C member 23)
Gene: SEC63

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	33957083, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 243 Hs			1 760
+	Hs
		1349636 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		SEC63_HUMAN (1-742): 0: 750: 100.00
+	Hs
		1245684 MSPD2_HUMAN (4-182): 2.15e-38: 141: 25.41		SEC63_HUMAN (1-742): 0: 750: 100.00
+	Sc
		541724 SCS2_YEAST (8-221): 1.47e-36: 130: 22.03		SEC63_YEAST (6-521): 5.25e-86: 287: 20.40
+	Hs
		1348096 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		DJB12_HUMAN (81-218): 1.24e-40: 155: 27.66
+	Hs
		310869 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		DJC16_HUMAN (74-166): 3.35e-24: 110: 33.33
+	Hs
		1349655 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		DJC16_HUMAN (74-166): 3.35e-24: 110: 33.33