HitPredict

Interactor 1: VAPB (O95292)
Vesicle-associated membrane protein-associated protein B/C (VAMP-B/VAMP-C) (VAMP-associated protein B/C) (VAP-B/VAP-C)
Gene: VAPB

Interactor 2: SNX6 (Q9UNH7)
Sorting nexin-6 (TRAF4-associated factor 2) [Cleaved into: Sorting nexin-6, N-terminally processed]
Gene: SNX6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0042803 - protein homodimerization activity
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 243 Hs			1 406
+	Hs
		310881 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		SNX5_HUMAN (13-405): 3.75e-112: 336: 64.38
+	Hs
		240323 VAPB_HUMAN (1-243): 2.23e-87: 260: 100.00		SNX2_HUMAN (16-404): 1.6e-93: 292: 21.31
+	Hs
		240449 VAPA_HUMAN (1-243): 1.03e-79: 241: 62.30		SNX2_HUMAN (16-404): 1.6e-93: 292: 21.31