HitPredict

Interactor 1: RASL1 (O95294)
RasGAP-activating-like protein 1 (RAS protein activator like 1) (Ras GTPase-activating-like protein)
Gene: RASAL1

Interactor 2: SH23A (Q9BRG2)
SH2 domain-containing protein 3A (Novel SH2-containing protein 1)
Gene: SH2D3A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	C2~SH2
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 804 Hs			1 576
+	Hs
		433821 DAB2P_HUMAN (127-681): 1.29e-110: 366: 20.25		LYN_HUMAN (3-256): 5.16e-66: 225: 11.61
+	Hs
		434065 NGAP_HUMAN (81-675): 1.48e-93: 319: 20.06		LYN_HUMAN (3-256): 5.16e-66: 225: 11.61
+	Hs
		411884 NGAP_HUMAN (81-675): 1.48e-93: 319: 20.06		LCK_HUMAN (3-256): 1.89e-59: 207: 14.23
+	Hs
		412315 SYGP1_HUMAN (81-633): 4.01e-81: 286: 19.29		FYN_HUMAN (3-256): 1.73e-68: 232: 13.76
+	Hs
		433572 NF1_HUMAN (219-682): 3.15e-77: 275: 20.76		LYN_HUMAN (3-256): 5.16e-66: 225: 11.61
+	Hs
		411593 NF1_HUMAN (219-682): 3.15e-77: 275: 20.76		LCK_HUMAN (3-256): 1.89e-59: 207: 14.23
+	Hs
		802705 SYGP1_HUMAN (81-633): 4.01e-81: 286: 19.29		CRK_HUMAN (3-246): 6.1e-51: 179: 21.17
+	Hs
		666184 NGAP_HUMAN (81-675): 1.48e-93: 319: 20.06		SHC1_HUMAN (1-117): 5.09e-32: 132: 32.26
+	Hs
		433461 SYT3_HUMAN (1-104): 1.83e-22: 104: 25.23		YES_HUMAN (3-256): 8.44e-68: 231: 12.36
+	Hs
		433383 SYT6_HUMAN (1-104): 2.64e-15: 81.7: 29.73		YES_HUMAN (3-256): 8.44e-68: 231: 12.36
+	Hs
		433762 RASA3_HUMAN (4-154): 2.56e-15: 82.2: 17.51		LYN_HUMAN (3-256): 5.16e-66: 225: 11.61
+	Hs
		433252 RASA1_HUMAN (1-288): 3.35e-13: 75.7: 14.14		YES_HUMAN (3-256): 8.44e-68: 231: 12.36
+	Hs
		522768 RASA1_HUMAN (1-288): 3.35e-13: 75.7: 14.14		SRC_HUMAN (3-256): 7.28e-68: 231: 12.36
+	Hs
		442830 RASA3_HUMAN (4-154): 2.56e-15: 82.2: 17.51		HCK_HUMAN (3-256): 5.43e-62: 215: 13.48
+	Hs
		442777 RASA1_HUMAN (1-288): 3.35e-13: 75.7: 14.14		HCK_HUMAN (3-256): 5.43e-62: 215: 13.48
+	Hs
		411591 RASA1_HUMAN (1-288): 3.35e-13: 75.7: 14.14		LCK_HUMAN (3-256): 1.89e-59: 207: 14.23
+	Hs
		337344 RASA1_HUMAN (1-288): 3.35e-13: 75.7: 14.14		ABL1_HUMAN (3-256): 8.1e-51: 190: 16.79
+	Mm
		93302 E9PYG6_MOUSE (1-288): 3.36e-13: 75.7: 14.14		ABL1_MOUSE (3-256): 2.33e-50: 189: 16.79
+	Hs
		596390 RASA1_HUMAN (1-288): 3.35e-13: 75.7: 14.14		GRB2_HUMAN (3-166): 7.35e-45: 159: 19.21
+	Hs
		580921 RASA1_HUMAN (1-288): 3.35e-13: 75.7: 14.14		PLCG1_HUMAN (2-254): 6.27e-34: 139: 18.42