HitPredict

Interactor 1: SNAPN (O95295)
SNARE-associated protein Snapin (Biogenesis of lysosome-related organelles complex 1 subunit 7) (BLOC-1 subunit 7) (Synaptosomal-associated protein 25-binding protein) (SNAP-associated protein)
Gene: SNAPIN

Interactor 2: TPM1 (P09493)
Tropomyosin alpha-1 chain (Alpha-tropomyosin) (Tropomyosin-1)
Gene: TPM1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	23414517
Identification Methods	two hybrid, two hybrid fragment pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 136 Hs			1 284
+	Hs
		310894 SNAPN_HUMAN (1-136): 4.66e-79: 231: 100.00		LAMC1_HUMAN (2-284): 2.65e-53: 188: 18.34
+	Hs
		310905 SNAPN_HUMAN (1-136): 4.66e-79: 231: 100.00		LAMA2_HUMAN (2-265): 1.15e-49: 178: 21.19
+	Hs
		310888 SNAPN_HUMAN (1-136): 4.66e-79: 231: 100.00		TPM3_HUMAN (1-284): 1.02e-43: 152: 91.20
+	Hs
		310889 SNAPN_HUMAN (1-136): 4.66e-79: 231: 100.00		TPM2_HUMAN (1-284): 1.39e-38: 138: 85.56
+	Hs
		310958 SNAPN_HUMAN (1-136): 4.66e-79: 231: 100.00		MRCKA_HUMAN (1-282): 1.08e-31: 126: 17.67
+	Hs
		310927 SNAPN_HUMAN (1-136): 4.66e-79: 231: 100.00		TPM4_HUMAN (42-284): 3.76e-33: 123: 68.72