HitPredict

Interactor 1: MPZL1 (O95297)
Myelin protein zero-like protein 1 (Protein zero-related)
Gene: MPZL1

Interactor 2: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.827

Property	Details
Experiments	30442766, 30639242, 30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~V-set
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 269 Hs			1 189
+	Hs
		311032 MPZL1_HUMAN (1-269): 6.16e-73: 225: 100.00		RASK_HUMAN (16-189): 7.56e-85: 249: 85.71
+	Hs
		311078 MPZL1_HUMAN (1-269): 6.16e-73: 225: 100.00		RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71
+	Hs
		311031 MPZL1_HUMAN (1-269): 6.16e-73: 225: 100.00		RASH_HUMAN (1-188): 8.6e-78: 232: 85.64
+	Hs
		311062 MPZL1_HUMAN (1-269): 6.16e-73: 225: 100.00		RAB2A_HUMAN (4-185): 1.53e-73: 222: 31.52
+	Hs
		350183 NECT1_HUMAN (10-268): 1.55e-44: 158: 15.33		RASK_HUMAN (16-189): 7.56e-85: 249: 85.71
+	Hs
		348518 MYP0_HUMAN (24-269): 5.93e-51: 168: 32.66		RASN_HUMAN (1-189): 9.9e-80: 236: 100.00
+	Hs
		348671 NECT1_HUMAN (10-268): 1.55e-44: 158: 15.33		RASN_HUMAN (1-189): 9.9e-80: 236: 100.00
+	Hs
		349330 NECT1_HUMAN (10-268): 1.55e-44: 158: 15.33		RASH_HUMAN (1-188): 8.6e-78: 232: 85.64
+	Hs
		234733 MPZL2_HUMAN (23-155): 3.11e-40: 140: 39.26		RASK_HUMAN (16-189): 7.56e-85: 249: 85.71
+	Hs
		350737 JAM1_HUMAN (9-253): 7.02e-39: 139: 13.88		RASK_HUMAN (16-189): 7.56e-85: 249: 85.71
+	Hs
		1070483 JAM1_HUMAN (9-253): 7.02e-39: 139: 13.88		RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71
+	Hs
		350058 CXAR_HUMAN (19-244): 1.52e-35: 132: 22.27		RASK_HUMAN (16-189): 7.56e-85: 249: 85.71
+	Hs
		349034 JAM1_HUMAN (9-253): 7.02e-39: 139: 13.88		RASN_HUMAN (1-189): 9.9e-80: 236: 100.00
+	Hs
		211414 SIGL6_HUMAN (32-264): 6.52e-39: 142: 10.68		RASH_HUMAN (1-188): 8.6e-78: 232: 85.64
+	Hs
		234732 MPZL2_HUMAN (23-155): 3.11e-40: 140: 39.26		RASH_HUMAN (1-188): 8.6e-78: 232: 85.64
+	Hs
		349767 JAM1_HUMAN (9-253): 7.02e-39: 139: 13.88		RASH_HUMAN (1-188): 8.6e-78: 232: 85.64
+	Hs
		348608 CXAR_HUMAN (19-244): 1.52e-35: 132: 22.27		RASN_HUMAN (1-189): 9.9e-80: 236: 100.00
+	Hs
		349237 CXAR_HUMAN (19-244): 1.52e-35: 132: 22.27		RASH_HUMAN (1-188): 8.6e-78: 232: 85.64
+	Hs
		895337 JAM1_HUMAN (9-253): 7.02e-39: 139: 13.88		RAB2A_HUMAN (4-185): 1.53e-73: 222: 31.52
+	Hs
		895030 CXAR_HUMAN (19-244): 1.52e-35: 132: 22.27		RAB2A_HUMAN (4-185): 1.53e-73: 222: 31.52