HitPredict

Interactor 1: MPZL1 (O95297)
Myelin protein zero-like protein 1 (Protein zero-related)
Gene: MPZL1

Interactor 2: PTN11 (Q06124)
Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1D) (PTP-1D) (Protein-tyrosine phosphatase 2C) (PTP-2C) (SH-PTP2) (SHP-2) (Shp2) (SH-PTP3)
Gene: PTPN11

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.50	0.633

Property	Details
Experiments	28514442, 9792637, 33961781, 10681522
Identification Methods	affinity chromatography technology, coimmunoprecipitation, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 269 Hs			1 593
+	Hs
		589567 CD33_HUMAN (38-263): 2.3e-40: 144: 10.44		PTN11_HUMAN (1-593): 0: 581: 100.00
+	Hs
		986060 SIGL7_HUMAN (38-263): 4.34e-39: 143: 12.17		PTN11_HUMAN (1-593): 0: 581: 100.00
+	Hs
		986062 SIGL9_HUMAN (34-263): 5.63e-39: 143: 12.77		PTN11_HUMAN (1-593): 0: 581: 100.00
+	Hs
		177596 SIGL5_HUMAN (37-264): 6.92e-38: 141: 15.02		PTN11_HUMAN (1-593): 0: 581: 100.00
+	Hs
		986013 SIG10_HUMAN (38-264): 7.29e-36: 136: 13.36		PTN11_HUMAN (1-593): 0: 581: 100.00
+	Rn
		783505 SHPS1_RAT (11-177): 5.78e-25: 105: 24.16		PTN11_RAT (1-593): 0: 578: 98.99
+	Hs
		589559 CD33_HUMAN (38-263): 2.3e-40: 144: 10.44		PTN6_HUMAN (6-593): 0: 531: 55.27
+	Hs
		665970 SIGL7_HUMAN (38-263): 4.34e-39: 143: 12.17		PTN6_HUMAN (6-593): 0: 531: 55.27
+	Hs
		665971 SIGL9_HUMAN (34-263): 5.63e-39: 143: 12.77		PTN6_HUMAN (6-593): 0: 531: 55.27
+	Hs
		177594 SIGL5_HUMAN (37-264): 6.92e-38: 141: 15.02		PTN6_HUMAN (6-593): 0: 531: 55.27
+	Hs
		665940 SIG10_HUMAN (38-264): 7.29e-36: 136: 13.36		PTN6_HUMAN (6-593): 0: 531: 55.27
+	Mm
		719295 SHPS1_MOUSE (11-172): 5.5e-17: 82.2: 20.81		PTN11_MOUSE (1-593): 0: 580: 99.49
+	Mm
		665983 SHPS1_MOUSE (11-172): 5.5e-17: 82.2: 20.81		PTN6_MOUSE (6-583): 0: 530: 55.94
+	Hs
		665857 SHPS1_HUMAN (38-176): 3.1e-14: 74.1: 25.17		PTN6_HUMAN (6-593): 0: 531: 55.27
+	Hs
		246337 SCN2B_HUMAN (9-217): 1.12e-45: 154: 25.59		PTPRD_HUMAN (39-522): 2.1e-115: 379: 26.76
+	Hs
		246335 SCN2B_HUMAN (9-217): 1.12e-45: 154: 25.59		PTPRF_HUMAN (33-522): 2.6e-112: 371: 25.85
+	Hs
		573657 CXAR_HUMAN (19-244): 1.52e-35: 132: 22.27		PTN1_HUMAN (232-541): 4.38e-110: 338: 31.63
+	Hs
		577011 SHPS1_HUMAN (38-176): 3.1e-14: 74.1: 25.17		PTPRA_HUMAN (33-522): 7.08e-110: 349: 23.72
+	Rn
		873519 SCN2B_RAT (9-216): 1.17e-42: 146: 25.71		PTPRZ_RAT (33-537): 3.94e-67: 239: 17.93
+	Rn
		962614 SCN1B_RAT (22-191): 1.28e-38: 136: 24.86		PTPRZ_RAT (33-537): 3.94e-67: 239: 17.93