Interactor 1: SIX3 (O95343)
Homeobox protein SIX3 (Sine oculis homeobox homolog 3)
Gene: SIX3

Interactor 2: PAX6 (P26367)
Paired box protein Pax-6 (Aniridia type II protein) (Oculorhombin)
Gene: PAX6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 11069920
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Homeodomain~Homeodomain, Homeodomain~SIX1_SD
Common GO terms GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001654 - eye development
and 8 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 332
Hs

1 422
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ Ce
+ Dm
+ Dm
+ Ce
+ Mm
+ Mm
+ Dm
+ Hs
+ Mm
+ Dm
+ Ce
+ Mm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024