Interactor 1: SIX3 (O95343)
Homeobox protein SIX3 (Sine oculis homeobox homolog 3)
Gene: SIX3
Interactor 2: PAX6 (P26367)
Paired box protein Pax-6 (Aniridia type II protein) (Oculorhombin)
Gene: PAX6
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.41 | 1.00 | 0.647 |
The method score is based on:
Property | Details |
---|---|
Experiments | 11069920 |
Identification Methods | pull down |
Interaction Type | direct interaction |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | Homeodomain~Homeodomain, Homeodomain~SIX1_SD |
Common GO terms | GO:0000785 - chromatin GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001654 - eye development and 8 others more... |
Homologous interactions | 18 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024