HitPredict

Interactor 1: SMC2 (O95347)
Structural maintenance of chromosomes protein 2 (SMC protein 2) (SMC-2) (Chromosome-associated protein E) (hCAP-E) (XCAP-E homolog)
Gene: SMC2

Interactor 2: SUMO2 (P61956)
Small ubiquitin-related modifier 2 (SUMO-2) (HSMT3) (SMT3 homolog 2) (SUMO-3) (Sentrin-2) (Ubiquitin-like protein SMT3B) (Smt3B)
Gene: SUMO2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	32786267, 34349018
Identification Methods	pull down, cross-linking study
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1197 Hs			1 95
+	Hs
		902772 SMC4_HUMAN (1-1176): 1.1e-87: 312: 17.32		SUMO2_HUMAN (1-95): 3.56e-44: 139: 100.00
+	Ce
		823187 DPY27_CAEEL (1-1196): 1.97e-81: 295: 15.12		SUMO_CAEEL (1-93): 1.11e-33: 113: 46.24
+	Hs
		902586 SMC1A_HUMAN (2-1181): 1.96e-73: 269: 17.18		SUMO2_HUMAN (1-95): 3.56e-44: 139: 100.00
+	Hs
		902813 SMC3_HUMAN (1-1187): 2.82e-73: 268: 18.01		SUMO2_HUMAN (1-95): 3.56e-44: 139: 100.00
+	Sc
		700812 SMC1_YEAST (2-1164): 5.85e-73: 268: 18.11		SMT3_YEAST (3-94): 4.25e-31: 106: 42.39
+	At
		878967 SMC1_ARATH (2-1172): 2.55e-67: 250: 15.06		SUMO1_ARATH (1-91): 8.61e-36: 118: 47.25
+	Sc
		1015401 SMC4_YEAST (1-1177): 4.88e-65: 244: 15.59		SMT3_YEAST (3-94): 4.25e-31: 106: 42.39