HitPredict

Interactor 1: SMC2 (O95347)
Structural maintenance of chromosomes protein 2 (SMC protein 2) (SMC-2) (Chromosome-associated protein E) (hCAP-E) (XCAP-E homolog)
Gene: SMC2

Interactor 2: FOXL1 (Q12952)
Forkhead box protein L1 (Forkhead-related protein FKHL11) (Forkhead-related transcription factor 7) (FREAC-7)
Gene: FOXL1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	25609649
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 1197 Hs			1 345
+	Hs
		1021360 SMC4_HUMAN (1-1176): 1.1e-87: 312: 17.32		FOXL1_HUMAN (1-345): 1.46e-108: 322: 100.00
+	Hs
		311609 SMC2_HUMAN (1-1197): 9.22e-128: 423: 100.00		FOXB1_HUMAN (38-315): 6.26e-51: 173: 29.14
+	Hs
		311512 SMC2_HUMAN (1-1197): 9.22e-128: 423: 100.00		FOXL2_HUMAN (40-138): 8.25e-50: 172: 66.67
+	Hs
		1021284 SMC1A_HUMAN (2-1181): 1.96e-73: 269: 17.18		FOXL1_HUMAN (1-345): 1.46e-108: 322: 100.00
+	Hs
		208882 SMC2_HUMAN (1-1197): 9.22e-128: 423: 100.00		FOXS1_HUMAN (38-240): 7.82e-49: 168: 41.38
+	Hs
		1021385 SMC3_HUMAN (1-1187): 2.82e-73: 268: 18.01		FOXL1_HUMAN (1-345): 1.46e-108: 322: 100.00
+	Hs
		877640 SMC4_HUMAN (1-1176): 1.1e-87: 312: 17.32		FOXG1_HUMAN (48-224): 2.13e-52: 182: 40.68
+	Hs
		126482 SMC4_HUMAN (1-1176): 1.1e-87: 312: 17.32		FOXE1_HUMAN (6-312): 1.36e-52: 179: 33.86
+	Hs
		1306870 SMC4_HUMAN (1-1176): 1.1e-87: 312: 17.32		FOXB1_HUMAN (38-315): 6.26e-51: 173: 29.14
+	Hs
		1021108 SMC1A_HUMAN (2-1181): 1.96e-73: 269: 17.18		FOXC1_HUMAN (9-280): 1.15e-53: 186: 35.86
+	Hs
		1021181 SMC3_HUMAN (1-1187): 2.82e-73: 268: 18.01		FOXC1_HUMAN (9-280): 1.15e-53: 186: 35.86
+	Hs
		877611 SMC1A_HUMAN (2-1181): 1.96e-73: 269: 17.18		FOXG1_HUMAN (48-224): 2.13e-52: 182: 40.68
+	Hs
		877649 SMC3_HUMAN (1-1187): 2.82e-73: 268: 18.01		FOXG1_HUMAN (48-224): 2.13e-52: 182: 40.68
+	Hs
		1057370 SMC1A_HUMAN (2-1181): 1.96e-73: 269: 17.18		FOXB1_HUMAN (38-315): 6.26e-51: 173: 29.14
+	Hs
		1306885 SMC3_HUMAN (1-1187): 2.82e-73: 268: 18.01		FOXB1_HUMAN (38-315): 6.26e-51: 173: 29.14