HitPredict

Interactor 1: SMC2 (O95347)
Structural maintenance of chromosomes protein 2 (SMC protein 2) (SMC-2) (Chromosome-associated protein E) (hCAP-E) (XCAP-E homolog)
Gene: SMC2

Interactor 2: CND2 (Q15003)
Condensin complex subunit 2 (Barren homolog protein 1) (Chromosome-associated protein H) (hCAP-H) (Non-SMC condensin I complex subunit H) (XCAP-H homolog)
Gene: NCAPH

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	1.00	0.952

The method score is based on:

Property	Details
Experiments	26496610, 26166704, 35271311, 36652389, 21633354, 17268547
Identification Methods	affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, pull down
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	Cnd2~SMC_N
Common GO terms	GO:0000794 - condensed nuclear chromosome GO:0000796 - condensin complex GO:0003682 - chromatin binding GO:0005654 - nucleoplasm GO:0005829 - cytosol and 6 others more... GO:0007076 - mitotic chromosome condensation GO:0010032 - meiotic chromosome condensation GO:0051301 - cell division GO:0051984 - positive regulation of chromosome segregation GO:1905820 - positive regulation of chromosome separation GO:1905821 - positive regulation of chromosome condensation
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1	1197
Hs

1	741

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024