Interactor 1: SMC2 (O95347)
Structural maintenance of chromosomes protein 2 (SMC protein 2) (SMC-2) (Chromosome-associated protein E) (hCAP-E) (XCAP-E homolog)
Gene: SMC2

Interactor 2: SMC4 (Q9NTJ3)
Structural maintenance of chromosomes protein 4 (SMC protein 4) (SMC-4) (Chromosome-associated polypeptide C) (hCAP-C) (XCAP-C homolog)
Gene: SMC4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.965

The method score is based on:

Property Details
Experiments 9789013, 26166704, 30021884, 34349018, 35235311, 37071682, 17113138, 17268547
Identification Methods affinity chromatography technology, proximity labelling technology, cross-linking study, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains SMC_hinge~SMC_hinge, SMC_N~SMC_N
Common GO terms GO:0000794 - condensed nuclear chromosome
GO:0000796 - condensin complex
GO:0003682 - chromatin binding
GO:0003697 - single-stranded DNA binding
GO:0005524 - ATP binding
and 12 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 1197
Hs

1 1288
+ Xl
+ Sp
+ Hs
+ Sc
+ Ce
+ Ce
+ Sc
+ Sc
+ Bs
+ Hs
+ Bt
+ Xl
+ Xl
+ Xl
+ Sp
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024