HitPredict

Interactor 1: ATG7 (O95352)
Ubiquitin-like modifier-activating enzyme ATG7 (ATG12-activating enzyme E1 ATG7) (Autophagy-related protein 7) (APG7-like) (hAGP7) (Ubiquitin-activating enzyme E1-like protein)
Gene: ATG7

Interactor 2: ATG7 (O95352)
Ubiquitin-like modifier-activating enzyme ATG7 (ATG12-activating enzyme E1 ATG7) (Autophagy-related protein 7) (APG7-like) (hAGP7) (Ubiquitin-activating enzyme E1-like protein)
Gene: ATG7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 11096062, 20562859
Identification Methods cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ATG7_N~ATG7_N, ThiF~ThiF
Common GO terms GO:0000045 - autophagosome assembly
GO:0000407 - phagophore assembly site
GO:0000423 - mitophagy
GO:0005576 - extracellular region
GO:0005737 - cytoplasm
and 22 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 703
Hs

1 703
+ Mm
+ Sc
+ Hs
+ Zm
+ Sc
+ Hs
+ Ec
+ Sc
+ Oc
+ Hs
+ Sp
+ Sc
+ Cj
+ Ec

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024