HitPredict

Interactor 1: ATG7 (O95352)
Ubiquitin-like modifier-activating enzyme ATG7 (ATG12-activating enzyme E1 ATG7) (Autophagy-related protein 7) (APG7-like) (hAGP7) (Ubiquitin-activating enzyme E1-like protein)
Gene: ATG7

Interactor 2: GBRL2 (P60520)
Gamma-aminobutyric acid receptor-associated protein-like 2 (GABA(A) receptor-associated protein-like 2) (Ganglioside expression factor 2) (GEF-2) (General protein transport factor p16) (Golgi-associated ATPase enhancer of 16 kDa) (GATE-16) (MAP1 light chain 3-related protein)
Gene: GABARAPL2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 1.00 0.886

The method score is based on:

Property Details
Experiments 16303767, 20562859, 11096062
Identification Methods enzymatic study, pull down, affinity chromatography technology, anti tag coimmunoprecipitation, comigration in non denaturing gel electrophoresis
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ATG8~ThiF
Common GO terms GO:0000045 - autophagosome assembly
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006914 - autophagy
GO:0006995 - cellular response to nitrogen starvation
and 1 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 703
Hs

1 117
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024