HitPredict

Interactor 1: ATG7 (O95352)
Ubiquitin-like modifier-activating enzyme ATG7 (ATG12-activating enzyme E1 ATG7) (Autophagy-related protein 7) (APG7-like) (hAGP7) (Ubiquitin-activating enzyme E1-like protein)
Gene: ATG7

Interactor 2: MLP3C (Q9BXW4)
Microtubule-associated proteins 1A/1B light chain 3C (Autophagy-related protein LC3 C) (Autophagy-related ubiquitin-like modifier LC3 C) (MAP1 light chain 3-like protein 3) (MAP1A/MAP1B light chain 3 C) (MAP1A/MAP1B LC3 C) (Microtubule-associated protein 1 light chain 3 gamma)
Gene: MAP1LC3C

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.825

The method score is based on:

Property Details
Experiments 20562859, 31857374
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains ATG8~ThiF
Common GO terms GO:0000045 - autophagosome assembly
GO:0005829 - cytosol
GO:0006995 - cellular response to nitrogen starvation
GO:0009267 - cellular response to starvation
GO:0016236 - macroautophagy
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 703
Hs

1 147
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024