Interactor 1: ATG7 (O95352)
Ubiquitin-like modifier-activating enzyme ATG7 (ATG12-activating enzyme E1 ATG7) (Autophagy-related protein 7) (APG7-like) (hAGP7) (Ubiquitin-activating enzyme E1-like protein)
Gene: ATG7

Interactor 2: MLP3B (Q9GZQ8)
Microtubule-associated proteins 1A/1B light chain 3B (Autophagy-related protein LC3 B) (Autophagy-related ubiquitin-like modifier LC3 B) (MAP1 light chain 3-like protein 2) (MAP1A/MAP1B light chain 3 B) (MAP1A/MAP1B LC3 B) (Microtubule-associated protein 1 light chain 3 beta)
Gene: MAP1LC3B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.962

The method score is based on:

Property Details
Experiments 15355958, 30806153, 31006538, 20562859, 24023838, 18083104, 16303767
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, pull down, comigration in non denaturing gel electrophoresis
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains ATG8~ThiF
Common GO terms GO:0000045 - autophagosome assembly
GO:0000423 - mitophagy
GO:0005829 - cytosol
GO:0005930 - axoneme
GO:0006914 - autophagy
and 3 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 703
Hs

1 125
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Mm
+ Mm
+ Mm
+ At
+ At
+ Dm
+ Ce
+ Ce
+ Sc
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024